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Angiotensin II type 2 receptor activation preserves megalin in the kidney and prevents proteinuria in high salt diet fed rats

Proteinuria is a risk factor for and consequence of kidney injury. Angiotensin II type 2 receptor (AT(2)R) is an emerging reno-protective target and is anti-proteinuric under pathological conditions, including high salt-fed obese animals. However, the mechanisms remain unknown, particularly whether...

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Detalles Bibliográficos
Autores principales: Kulkarni, Kalyani, Patel, Sanket, Ali, Riyasat, Hussain, Tahir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017765/
https://www.ncbi.nlm.nih.gov/pubmed/36922642
http://dx.doi.org/10.1038/s41598-023-31454-6