MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas

The paracaspase mucosa-associated lymphoid tissue 1 (MALT1) is a protease and scaffold protein essential in propagating B-cell receptor (BCR) signaling to NF-κB. The deubiquitinating enzyme cylindromatosis (CYLD) is a recently discovered MALT1 target that can negatively regulate NF-κB activation. He...

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Detalles Bibliográficos
Autores principales: Minderman, Marthe, Lantermans, Hildo C., Grüneberg, Leonie J., Cillessen, Saskia A. G. M., Bende, Richard J., van Noesel, Carel J. M., Kersten, Marie José, Pals, Steven T., Spaargaren, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017792/
https://www.ncbi.nlm.nih.gov/pubmed/36922488
http://dx.doi.org/10.1038/s41408-023-00809-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017792/
https://www.ncbi.nlm.nih.gov/pubmed/36922488
http://dx.doi.org/10.1038/s41408-023-00809-7

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