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Reelin and APP Cooperatively Modulate Dendritic Spine Formation In Vitro and In Vivo

Amyloid precursor protein (APP) plays an important role in the pathogenesis of Alzheimer’s disease (AD), but the normal function of APP at synapses is poorly understood. We and others have found that APP interacts with Reelin and that each protein is individually important for dendritic spine format...

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Detalles Bibliográficos
Autores principales: Lee, Hyun-ju, Park, Jin-Hee, Trotter, Justin H., Maher, James N., Keenoy, Kathleen E., Jang, You Mi, Lee, Youngeun, Kim, Jae-Ick, Weeber, Edwin J., Hoe, Hyang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017845/
https://www.ncbi.nlm.nih.gov/pubmed/36919335
http://dx.doi.org/10.5607/en22044