Mutating both relA and spoT of enteropathogenic Escherichia coli E2348/69 attenuates its virulence and induces interleukin 6 in vivo

Here, we report for the first time that disrupting both relA and spoT genes in enteropathogenic Escherichia coli E2348/69 can attenuate its virulence and significantly induce interleukin 6 (IL-6) in vivo. Our experimental analyses demonstrated that an E2348/69 ΔrelAΔspoT double mutant strain derepre...

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Detalles Bibliográficos
Autores principales: Lee, Jun Bong, Kim, Se Kye, Han, Dalmuri, Yoon, Jang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017862/
https://www.ncbi.nlm.nih.gov/pubmed/36937293
http://dx.doi.org/10.3389/fmicb.2023.1121715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017862/
https://www.ncbi.nlm.nih.gov/pubmed/36937293
http://dx.doi.org/10.3389/fmicb.2023.1121715

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