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β-Lactam Resistance in ESKAPE Pathogens Mediated Through Modifications in Penicillin-Binding Proteins: An Overview

Bacteria acquire β-lactam resistance through a multitude of mechanisms among which production of β-lactamases (enzymes that hydrolyze β-lactams) is the most common, especially in Gram-negatives. Structural changes in the high-molecular-weight, essential penicillin-binding proteins (PBPs) are widespr...

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Detalles Bibliográficos
Autores principales: Sethuvel, Dhiviya Prabaa Muthuirulandi, Bakthavatchalam, Yamuna Devi, Karthik, Maruthan, Irulappan, Madhumathi, Shrivastava, Rahul, Periasamy, Hariharan, Veeraraghavan, Balaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017896/
https://www.ncbi.nlm.nih.gov/pubmed/36877435
http://dx.doi.org/10.1007/s40121-023-00771-8