Packaging cells for lentiviral vectors generated using the cumate and coumermycin gene induction systems and nanowell single-cell cloning

Lentiviral vectors (LVs) are important for cell therapy because of their capacity to stably modify the genome after integration. This study describes a novel and relatively simple approach to generate packaging cells and producer clones for self-inactivating (SIN) LVs pseudotyped with the vesicular...

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Detalles Bibliográficos
Autores principales: Broussau, Sophie, Lytvyn, Viktoria, Simoneau, Mélanie, Guilbault, Claire, Leclerc, Mélanie, Nazemi-Moghaddam, Nazila, Coulombe, Nathalie, Elahi, Seyyed Mehdy, McComb, Scott, Gilbert, Rénald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018046/
https://www.ncbi.nlm.nih.gov/pubmed/36936448
http://dx.doi.org/10.1016/j.omtm.2023.02.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018046/
https://www.ncbi.nlm.nih.gov/pubmed/36936448
http://dx.doi.org/10.1016/j.omtm.2023.02.013

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