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Artemisinin exerts a protective effect in the MPTP mouse model of Parkinson's disease by inhibiting microglial activation via the TLR4/Myd88/NF‐KB pathway

AIMS: We performed cell and animal experiments to explore the therapeutic effect of artemisinin on Parkinson's disease (PD) and the TLR4/Myd88 signaling pathway. METHODS: C57 mice were randomly divided into the blank, 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐induced and artemisinin‐t...

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Detalles Bibliográficos
Autores principales: Lv, Jing, Zhu, Jing, Wang, Peihan, Liu, Tongyu, Yuan, Jiang, Yin, Huan, Lan, Yiran, Sun, Qiang, Zhang, Zhifeng, Ding, Guoda, Zhou, Chenxi, Wang, Huajie, Wang, Zihan, Wang, Yunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018080/
https://www.ncbi.nlm.nih.gov/pubmed/36691817
http://dx.doi.org/10.1111/cns.14063