Patient-derived podocyte spheroids reveal new insights into the etiopathogenesis of Alport syndrome

Alport syndrome (AS) is a rare disease characterized by defective glomerular basement membranes, caused by mutations in COL4A3, COL4A4, and COL4A5, which synthesize collagen type IV. Patients present with progressive proteinuria, hematuria and podocyte loss. There is currently no cure for Alport syn...

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Detalles Bibliográficos
Autores principales: Romero-Guevara, Ricardo, Nicolaou, Orthodoxia, Petracca, Benedetta, Shaheed, Sadr, Sutton, Christopher, Frangou, Eleni, Afami, Marina, Kyriacou, Kyriacos, Ioannides, Adonis, Xinaris, Christodoulos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018139/
https://www.ncbi.nlm.nih.gov/pubmed/36936689
http://dx.doi.org/10.3389/fcell.2023.1111424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018139/
https://www.ncbi.nlm.nih.gov/pubmed/36936689
http://dx.doi.org/10.3389/fcell.2023.1111424

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