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STAT3 inhibitor Stattic and its analogues inhibit STAT3 phosphorylation and modulate cytokine secretion in senescent tumour cells

Signal transducer and activator of transcription 3 (STAT3) signalling serves an important role in carcinogenesis and cellular senescence, and its inhibition in tumour cells represents an attractive therapeutic target. Premature cellular senescence, a process of permanent proliferative arrest of cell...

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Detalles Bibliográficos
Autores principales: Mikyskova, Romana, Sapega, Olena, Psotka, Miroslav, Novotny, Ondrej, Hodny, Zdeněk, Balintova, Sona, Malinak, David, Svobodova, Jana, Andrys, Rudolf, Rysanek, David, Musilek, Kamil, Reinis, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018236/
https://www.ncbi.nlm.nih.gov/pubmed/36825563
http://dx.doi.org/10.3892/mmr.2023.12968