Hsc70 rescues the synaptic vesicle trafficking defects caused by α-synuclein dimers

Aberrant buildup of α-synuclein is associated with Parkinson’s disease (PD) and other neurodegenerative disorders. At synapses, α-synuclein accumulation leads to severe synaptic vesicle trafficking defects. We previously demonstrated that different molecular species of α-synuclein produce distinct e...

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Detalles Bibliográficos
Autores principales: Brady, Emily B., McQuillan, Molly, Medeiros, Audrey T., Bubacco, Luigi, Sousa, Rui, Lafer, Eileen M., Morgan, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018313/
https://www.ncbi.nlm.nih.gov/pubmed/36938331
http://dx.doi.org/10.17912/micropub.biology.000737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018313/
https://www.ncbi.nlm.nih.gov/pubmed/36938331
http://dx.doi.org/10.17912/micropub.biology.000737

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