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Structure of the Caenorhabditis elegans m(6)A methyltransferase METT10 that regulates SAM homeostasis
In Caenorhabditis elegans, the N(6)-methyladenosine (m(6)A) modification by METT10, at the 3'-splice sites in S-adenosyl-l-methionine (SAM) synthetase (sams) precursor mRNA (pre-mRNA), inhibits sams pre-mRNA splicing, promotes alternative splicing coupled with nonsense-mediated decay of the pre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018337/ https://www.ncbi.nlm.nih.gov/pubmed/36794723 http://dx.doi.org/10.1093/nar/gkad081 |