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Structure of the Caenorhabditis elegans m(6)A methyltransferase METT10 that regulates SAM homeostasis

In Caenorhabditis elegans, the N(6)-methyladenosine (m(6)A) modification by METT10, at the 3'-splice sites in S-adenosyl-l-methionine (SAM) synthetase (sams) precursor mRNA (pre-mRNA), inhibits sams pre-mRNA splicing, promotes alternative splicing coupled with nonsense-mediated decay of the pre...

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Detalles Bibliográficos
Autores principales: Ju, Jue, Aoyama, Tomohiko, Yashiro, Yuka, Yamashita, Seisuke, Kuroyanagi, Hidehito, Tomita, Kozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018337/
https://www.ncbi.nlm.nih.gov/pubmed/36794723
http://dx.doi.org/10.1093/nar/gkad081