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LINE-1 retrotransposon expression in cancerous, epithelial and neuronal cells revealed by 5′ single-cell RNA-Seq

LINE-1 retrotransposons are sequences capable of copying themselves to new genomic loci via an RNA intermediate. New studies implicate LINE-1 in a range of diseases, especially in the context of aging, but without an accurate understanding of where and when LINE-1 is expressed, a full accounting of...

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Detalles Bibliográficos
Autores principales: McKerrow, Wilson, Kagermazova, Larisa, Doudican, Nicole, Frazzette, Nicholas, Kaparos, Efiyenia Ismini, Evans, Shane A, Rocha, Azucena, Sedivy, John M, Neretti, Nicola, Carucci, John, Boeke, Jef D, Fenyö, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018344/
https://www.ncbi.nlm.nih.gov/pubmed/36744437
http://dx.doi.org/10.1093/nar/gkad049