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Trans-cis isomerization kinetics of cyanine dyes reports on the folding states of exogeneous RNA G-quadruplexes in live cells

Guanine (G)-rich nucleic acids are prone to assemble into four-stranded structures, so-called G-quadruplexes. Abnormal GGGGCC repeat elongations, and in particular their folding states, are associated with amyotrophic lateral sclerosis and frontotemporal dementia. Due to methodological constraints h...

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Detalles Bibliográficos
Autores principales: Kitamura, Akira, Tornmalm, Johan, Demirbay, Baris, Piguet, Joachim, Kinjo, Masataka, Widengren, Jerker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018373/
https://www.ncbi.nlm.nih.gov/pubmed/36651281
http://dx.doi.org/10.1093/nar/gkac1255