Seneca Valley virus replicons are packaged in trans and have the capacity to overcome the limitations of viral transgene expression

Oncolytic viruses (OVs) promote the anti-tumor immune response as their replication, and the subsequent lysis of tumor cells, triggers the activation of immune-sensing pathways. Arming OVs by expressing transgenes with the potential to promote immune cell recruitment and activation is an attractive...

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Detalles Bibliográficos
Autores principales: Bryant, Jeffrey D., Lee, Jennifer S., De Almeida, Ana, Jacques, Judy, Chang, Ching-Hung, Fassler, William, Quéva, Christophe, Lerner, Lorena, Kennedy, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018389/
https://www.ncbi.nlm.nih.gov/pubmed/36938543
http://dx.doi.org/10.1016/j.omto.2023.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018389/
https://www.ncbi.nlm.nih.gov/pubmed/36938543
http://dx.doi.org/10.1016/j.omto.2023.02.005

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