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Seneca Valley virus replicons are packaged in trans and have the capacity to overcome the limitations of viral transgene expression
Oncolytic viruses (OVs) promote the anti-tumor immune response as their replication, and the subsequent lysis of tumor cells, triggers the activation of immune-sensing pathways. Arming OVs by expressing transgenes with the potential to promote immune cell recruitment and activation is an attractive...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018389/ https://www.ncbi.nlm.nih.gov/pubmed/36938543 http://dx.doi.org/10.1016/j.omto.2023.02.005 |