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Tetramodal Chemical Imaging Delineates the Lipid–Amyloid Peptide Interplay at Single Plaques in Transgenic Alzheimer’s Disease Models

[Image: see text] Beta-amyloid (Aβ) plaque pathology is one of the most prominent histopathological feature of Alzheimer’s disease (AD). The exact pathogenic mechanisms linking Aβ to AD pathogenesis remain however not fully understood. Recent advances in amyloid-targeting pharmacotherapies highlight...

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Detalles Bibliográficos
Autores principales: Ge, Junyue, Koutarapu, Srinivas, Jha, Durga, Dulewicz, Maciej, Zetterberg, Henrik, Blennow, Kaj, Hanrieder, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018455/
https://www.ncbi.nlm.nih.gov/pubmed/36856542
http://dx.doi.org/10.1021/acs.analchem.2c05302