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Improvements and challenges of tissue preparation for spatial transcriptome analysis of skull base tumors

BACKGROUND: Spatial transcriptome (ST) provides molecular profiles of tumor cells at the spatial level, which brings new progress to the research of tumors and the tumor microenvironment. This study summarizes the experiences and lessons learned in the spatial section preparation of two different pa...

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Detalles Bibliográficos
Autores principales: Fang, Yan, Peng, Zhouying, Wang, Yumin, Yuan, Xiaotian, Gao, Kelei, Fan, Ruohao, Liu, Ruijie, Liu, Yalan, Zhang, Hua, Xie, Zhihai, Jiang, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018477/
https://www.ncbi.nlm.nih.gov/pubmed/36938455
http://dx.doi.org/10.1016/j.heliyon.2023.e14133