Cargando…

Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat Alzheimer’s Disease

[Image: see text] A series of some novel compounds (SD-1–17) were designed following a molecular hybridization approach, synthesized, and biologically tested for hAChE, hBChE, hBACE-1, and Aβ aggregation inhibition potential to improve cognition and memory functions associated with Alzheimer’s disea...

Descripción completa

Detalles Bibliográficos
Autores principales: Waiker, Digambar Kumar, Verma, Akash, Saraf, Poorvi, T.A., Gajendra, Krishnamurthy, Sairam, Chaurasia, Rameshwar Nath, Shrivastava, Sushant Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018501/
https://www.ncbi.nlm.nih.gov/pubmed/36936338
http://dx.doi.org/10.1021/acsomega.2c08061