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Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat Alzheimer’s Disease
[Image: see text] A series of some novel compounds (SD-1–17) were designed following a molecular hybridization approach, synthesized, and biologically tested for hAChE, hBChE, hBACE-1, and Aβ aggregation inhibition potential to improve cognition and memory functions associated with Alzheimer’s disea...
Autores principales: | Waiker, Digambar Kumar, Verma, Akash, Saraf, Poorvi, T.A., Gajendra, Krishnamurthy, Sairam, Chaurasia, Rameshwar Nath, Shrivastava, Sushant Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018501/ https://www.ncbi.nlm.nih.gov/pubmed/36936338 http://dx.doi.org/10.1021/acsomega.2c08061 |
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