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Design and Evaluation of Ambiphilic Aryl Thiol–Iminium-Based Molecules for Organocatalyzed Thioacyl Aminolysis
[Image: see text] Progress toward the design and synthesis of ambiphilic aryl thiol–iminium-based small molecules for organocatalyzed thioacyl aminolysis is reported. Here we describe the synthesis of a novel tetrahydroisoquinoline-derived scaffold, bearing both thiol and iminium functionalities, ca...
Autores principales: | Digal, Lori D., Kirkeby, Emily K., Austin, Maxwell J., Roberts, Andrew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018527/ https://www.ncbi.nlm.nih.gov/pubmed/36936301 http://dx.doi.org/10.1021/acsomega.2c07586 |
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