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Polymorphism in interferon alpha/beta receptor contributes to glucocorticoid response and outcome of ARDS and COVID-19

BACKGROUND: The use of glucocorticoids has given contradictory results for treating acute respiratory distress syndrome (ARDS). The use of intravenous Interferon beta (IFN β) for the treatment of ARDS was recently tested in a phase III ARDS trial (INTEREST), in which more than half of the patients s...

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Detalles Bibliográficos
Autores principales: Jalkanen, Juho, Khan, Sofia, Elima, Kati, Huttunen, Teppo, Wang, Ning, Hollmén, Maija, Elo, Laura L., Jalkanen, Sirpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018638/
https://www.ncbi.nlm.nih.gov/pubmed/36927455
http://dx.doi.org/10.1186/s13054-023-04388-8