Early DNase-I therapy delays secondary brain damage after traumatic brain injury in adult mice

Traumatic brain injury (TBI) causes the release of danger-associated molecular patterns (DAMP) from damaged or dead cells, which contribute to secondary brain damage after TBI. Cell-free DNA (cfDNA) is a DAMP known to cause disruption of the blood–brain barrier (BBB), promote procoagulant processes,...

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Detalles Bibliográficos
Autores principales: Krämer, Tobias J., Pickart, Florian, Pöttker, Bruno, Gölz, Christina, Neulen, Axel, Pantel, Tobias, Goetz, Hermann, Ritter, Katharina, Schäfer, Michael K. E., Thal, Serge C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018640/
https://www.ncbi.nlm.nih.gov/pubmed/36928073
http://dx.doi.org/10.1038/s41598-023-30421-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018640/
https://www.ncbi.nlm.nih.gov/pubmed/36928073
http://dx.doi.org/10.1038/s41598-023-30421-5

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