Identification, Synthesis, and Characterization of Novel Baricitinib Impurities

[Image: see text] Baricitinib is a novel active pharmaceutical ingredient used in the treatment of rheumatoid arthritis, and it acts as an inhibitor of Janus kinase. During the synthesis of baricitinib, three unknown impurities were identified in several batches between 0.10 and 0.15% using high-per...

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Detalles Bibliográficos
Autores principales: Vaddamanu, Guruswamy, Goswami, Anandarup, Reddy, N. Ravi Sekhar, Kumar Reddy, Katam Reddy Vinod, Mulakayala, Naveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018714/
https://www.ncbi.nlm.nih.gov/pubmed/36936292
http://dx.doi.org/10.1021/acsomega.3c00100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018714/
https://www.ncbi.nlm.nih.gov/pubmed/36936292
http://dx.doi.org/10.1021/acsomega.3c00100

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