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Decrease in naturally occurring antibodies against epitopes of Alzheimer’s disease (AD) risk gene products is associated with cognitive decline in AD

BACKGROUND: Naturally occurring antibodies (NAbs) are germline-encoded immunoglobulins that can bind to and clear out self-neo-epitopes as well as apoptotic and necrotic cells. However, NAbs pathological relevance in Alzheimer’s disease (AD) is not well-understood. METHODS: Twenty-eight candidate pr...

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Detalles Bibliográficos
Autores principales:	Gu, Dongmei, Wang, Luchun, Zhang, Nan, Wang, Huali, Yu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018846/ https://www.ncbi.nlm.nih.gov/pubmed/36922858 http://dx.doi.org/10.1186/s12974-023-02750-9

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