NOMe-HiC: joint profiling of genetic variant, DNA methylation, chromatin accessibility, and 3D genome in the same DNA molecule

Cis-regulatory elements are coordinated to regulate the expression of their targeted genes. However, the joint measurement of cis-regulatory elements’ activities and their interactions in spatial proximity is limited by the current sequencing approaches. We describe a method, NOMe-HiC, which simulta...

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Detalles Bibliográficos
Autores principales: Fu, Hailu, Zheng, Haizi, Chen, Xiaoting, Weirauch, Matthew T., Muglia, Louis J., Wang, Li, Liu, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018866/
https://www.ncbi.nlm.nih.gov/pubmed/36927507
http://dx.doi.org/10.1186/s13059-023-02889-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018866/
https://www.ncbi.nlm.nih.gov/pubmed/36927507
http://dx.doi.org/10.1186/s13059-023-02889-x

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