Gut microbiota mediated the individualized efficacy of Temozolomide via immunomodulation in glioma

BACKGROUND: Temozolomide (TMZ) is the preferred chemotherapy strategy for glioma therapy. As a second-generation alkylating agent, TMZ provides superior oral bio-availability. However, limited response rate (less than 50%) and high incidence of drug resistance seriously restricts TMZ’s application,...

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Detalles Bibliográficos
Autores principales: Hou, Xiaoying, Du, Hongzhi, Deng, Yufei, Wang, Haiping, Liu, Jinmi, Qiao, Jialu, Liu, Wei, Shu, Xiji, Sun, Binlian, Liu, Yuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018922/
https://www.ncbi.nlm.nih.gov/pubmed/36927689
http://dx.doi.org/10.1186/s12967-023-04042-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018922/
https://www.ncbi.nlm.nih.gov/pubmed/36927689
http://dx.doi.org/10.1186/s12967-023-04042-5

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