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Involvement of KCa3.1 channel activity in immediate perioperative cognitive and neuroinflammatory outcomes

BACKGROUND: Potassium channels (KCa3.1; Kv1.3; Kir2.1) are necessary for microglial activation, a pivotal requirement for the development of Perioperative Neurocognitive Disorders (PNDs). We previously reported on the role of microglial Kv1.3 for PNDs; the present study sought to determine whether i...

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Detalles Bibliográficos
Autores principales: Saxena, Sarah, Nuyens, Vincent, Rodts, Christopher, Jamar, Kristina, Albert, Adelin, Seidel, Laurence, Cherkaoui-Malki, Mustapha, Boogaerts, Jean G., Wulff, Heike, Maze, Mervyn, Kruys, Véronique, Vamecq, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018926/
https://www.ncbi.nlm.nih.gov/pubmed/36927341
http://dx.doi.org/10.1186/s12871-023-02030-2