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Remote ischemic preconditioning protects against spinal cord ischemia–reperfusion injury in mice by activating NMDAR/AMPK/PGC-1α/SIRT3 signaling

BACKGROUND: To study the protective effects of delayed remote ischemic preconditioning (RIPC) against spinal cord ischemia–reperfusion injury (SCIRI) in mice and determine whether SIRT3 is involved in this protection and portrayed its upstream regulatory mechanisms. METHODS: In vivo, WT or SIRT3 glo...

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Detalles Bibliográficos
Autores principales: Gu, Changjiang, Kong, Fanqi, Zeng, Junkai, Geng, Xiangwu, Sun, Yanqing, Chen, Xiongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018930/
https://www.ncbi.nlm.nih.gov/pubmed/36927808
http://dx.doi.org/10.1186/s13578-023-00999-4