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Effects of CFTR modulators on serum biomarkers of liver fibrosis in children with cystic fibrosis

The cystic fibrosis (CF) transmembrane conductance regulator corrector/potentiator combinations lumacaftor/ivacaftor and elexacaftor/tezacaftor/ivacaftor improve sweat chloride, pulmonary function, and nutrition. Yet it is unclear whether they may also impact the progression of liver fibrosis, which...

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Detalles Bibliográficos
Autores principales: Levitte, Steven, Fuchs, Yonathan, Wise, Russell, Sellers, Zachary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019140/
https://www.ncbi.nlm.nih.gov/pubmed/36662672
http://dx.doi.org/10.1097/HC9.0000000000000010