Killing Two Birds with One Stone: Discovery of Dual Inhibitors of Oxygen and Fumarate Respiration in Zoonotic Parasite, Echinococcus multilocularis

Ascofuranone (AF), a meroterpenoid isolated from various filamentous fungi, including Acremonium egyptiacum, has been reported as a potential lead candidate for drug development against parasites and cancer. In this study, we demonstrated that AF and its derivatives are potent anthelminthic agents,...

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Detalles Bibliográficos
Autores principales: Enkai, Shigehiro, Kouguchi, Hirokazu, Inaoka, Daniel Ken, Shiba, Tomoo, Hidaka, Masahito, Matsuyama, Hiroyuki, Sakura, Takaya, Yagi, Kinpei, Kita, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Chemistry; Biosynthesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019194/
https://www.ncbi.nlm.nih.gov/pubmed/36840588
http://dx.doi.org/10.1128/aac.01428-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019194/
https://www.ncbi.nlm.nih.gov/pubmed/36840588
http://dx.doi.org/10.1128/aac.01428-22

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