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Repeated Emergence of Variant TetR Family Regulator, FarR, and Increased Resistance to Antimicrobial Unsaturated Fatty Acid among Clonal Complex 5 Methicillin-Resistant Staphylococcus aureus

Resistance-nodulation-division (RND) superfamily efflux pumps promote antibiotic resistance in Gram-negative pathogens, but their role in Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) is undocumented. However, recent in vitro selections for resistance of S. au...

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Detalles Bibliográficos
Autores principales: Bonn, Camryn M., Rafiqullah, Iftekhar M., Crawford, John A., Qian, Yi Meng, Guthrie, Jennifer L., Matuszewska, Marta, Robinson, D. Ashley, McGavin, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019231/
https://www.ncbi.nlm.nih.gov/pubmed/36744906
http://dx.doi.org/10.1128/aac.00749-22