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XerC Is Required for the Repair of Antibiotic- and Immune-Mediated DNA Damage in Staphylococcus aureus

To survive in the host environment, pathogenic bacteria need to be able to repair DNA damage caused by both antibiotics and the immune system. The SOS response is a key bacterial pathway to repair DNA double-strand breaks and may therefore be a good target for novel therapeutics to sensitize bacteri...

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Detalles Bibliográficos
Autores principales: Ledger, Elizabeth V. K., Lau, Katie, Tate, Edward W., Edwards, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019262/
https://www.ncbi.nlm.nih.gov/pubmed/36802166
http://dx.doi.org/10.1128/aac.01206-22