The Effect of β-Lactam Antibiotics on the Evolution of Ceftazidime/Avibactam and Cefiderocol Resistance in KPC-Producing Klebsiella pneumoniae

In this study, we aimed to clarify the evolutionary trajectory of a Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-Kp) population during β-lactam antibiotic therapy. Five KPC-Kp isolates were collected from a single patient. Whole-genome sequencing and a comparative g...

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Detalles Bibliográficos
Autores principales: Zhang, Ping, Hu, Huangdu, Shi, Qiucheng, Sun, Long, Wu, Xueqing, Hua, Xiaoting, McNally, Alan, Jiang, Yan, Yu, Yunsong, Du, Xiaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019305/
https://www.ncbi.nlm.nih.gov/pubmed/36794957
http://dx.doi.org/10.1128/aac.01279-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019305/
https://www.ncbi.nlm.nih.gov/pubmed/36794957
http://dx.doi.org/10.1128/aac.01279-22

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