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Future directions for medicinal chemistry in the field of oligonucleotide therapeutics
In the last decade, the field of oligonucleotide therapeutics has matured, with the regulatory approval of several single-stranded and double-stranded RNA drugs. In this Perspective, I discuss enabling developments and likely future directions in the field from the perspective of oligonucleotide che...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019366/ https://www.ncbi.nlm.nih.gov/pubmed/36693762 http://dx.doi.org/10.1261/rna.079511.122 |