Understanding repertoire sequencing data through a multiscale computational model of the germinal center

Sequencing of B-cell and T-cell immune receptor repertoires helps us to understand the adaptive immune response, although it only provides information about the clonotypes (lineages) and their frequencies and not about, for example, their affinity or antigen (Ag) specificity. To further characterize...

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Detalles Bibliográficos
Autores principales: García-Valiente, Rodrigo, Merino Tejero, Elena, Stratigopoulou, Maria, Balashova, Daria, Jongejan, Aldo, Lashgari, Danial, Pélissier, Aurélien, Caniels, Tom G., Claireaux, Mathieu A. F., Musters, Anne, van Gils, Marit J., Rodríguez Martínez, María, de Vries, Niek, Meyer-Hermann, Michael, Guikema, Jeroen E. J., Hoefsloot, Huub, van Kampen, Antoine H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019394/
https://www.ncbi.nlm.nih.gov/pubmed/36927990
http://dx.doi.org/10.1038/s41540-023-00271-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019394/
https://www.ncbi.nlm.nih.gov/pubmed/36927990
http://dx.doi.org/10.1038/s41540-023-00271-y

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