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Rapid plugged flow synthesis of nucleoside analogues via Suzuki-Miyaura coupling and heck Alkenylation of 5-Iodo-2’-deoxyuridine (or cytidine)

Nucleosides modification via conventional cross-coupling has been performed using different catalytic systems and found to take place via long reaction times. However, since the pandemic, nucleoside-based antivirals and vaccines have received widespread attention and the requirement for rapid modifi...

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Detalles Bibliográficos
Autores principales: Gaware, Sujeet, Kori, Santosh, Serrano, Jose Luis, Dandela, Rambabu, Hilton, Stephen, Sanghvi, Yogesh S., Kapdi, Anant R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019434/
https://www.ncbi.nlm.nih.gov/pubmed/37359287
http://dx.doi.org/10.1007/s41981-023-00265-1