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High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts

The fine structure of heparan sulfate (HS), the glycosaminoglycan polysaccharide component of cell surface and extracellular matrix HS proteoglycans, coordinates the complex cell signalling processes that control homeostasis and drive development in multicellular animals. In addition, HS is involved...

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Detalles Bibliográficos
Autores principales: Maciej-Hulme, Marissa L., Leprince, Anaëlle C. N., Lavin, Andre, Guimond, Scott E., Turnbull, Jeremy E., Pelletier, Julien, Yates, Edwin A., Powell, Andrew K., Skidmore, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019443/
https://www.ncbi.nlm.nih.gov/pubmed/36876452
http://dx.doi.org/10.1039/d2ay01803a