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Characterizing in vivo loss of virulence of an HN878 Mycobacterium tuberculosis isolate from a genetic duplication event

The increase of global cases of drug resistant (DR) Mycobacterium tuberculosis (M.tb) is a serious problem for the tuberculosis research community and the goals to END TB by 2030. Due to the need for advancing and screening next generation therapeutics and vaccines, we aimed to design preclinical DR...

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Detalles Bibliográficos
Autores principales: Berube, Bryan J., Larsen, Sasha E., McNeil, Matthew B., Reese, Valerie A., Pecor, Tiffany, Kaur, Suhavi, Parish, Tanya, Baldwin, Susan L., Coler, Rhea N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019580/
https://www.ncbi.nlm.nih.gov/pubmed/36375278
http://dx.doi.org/10.1016/j.tube.2022.102272