Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues

3D cell culture models of cancer are currently being developed to recapitulate in vivo physiological conditions and to assess therapeutic responses. However, most models failed to incorporate the biochemical and biophysical stimuli from fluid flow. In this study, a three-dimensional scaffold, SeedEZ...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Roberts, Sophie, Shoemaker, James T, Vukasinovic, Jelena, Tomlinson, Darren C, Speirs, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019722/
https://www.ncbi.nlm.nih.gov/pubmed/36928454
http://dx.doi.org/10.1371/journal.pone.0283044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019722/
https://www.ncbi.nlm.nih.gov/pubmed/36928454
http://dx.doi.org/10.1371/journal.pone.0283044

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