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Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues
3D cell culture models of cancer are currently being developed to recapitulate in vivo physiological conditions and to assess therapeutic responses. However, most models failed to incorporate the biochemical and biophysical stimuli from fluid flow. In this study, a three-dimensional scaffold, SeedEZ...
Autores principales: | Liu, Peng, Roberts, Sophie, Shoemaker, James T, Vukasinovic, Jelena, Tomlinson, Darren C, Speirs, Valerie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019722/ https://www.ncbi.nlm.nih.gov/pubmed/36928454 http://dx.doi.org/10.1371/journal.pone.0283044 |
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