Neonatal administration of synthetic estrogen, diethylstilbestrol to mice up-regulates inflammatory Cxclchemokines located in the 5qE1 region in the vaginal epithelium

A synthetic estrogen, diethylstilbestrol (DES), is known to cause adult vaginal carcinoma by neonatal administration of DES to mice. However, the carcinogenic process remains unclear. By Cap Analysis of Gene Expression method, we found that neonatal DES exposure up-regulated inflammatory Cxcl chemok...

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Detalles Bibliográficos
Autores principales: Kitamura, Ayaka, Jiayue, Chen, Suwa, Tomoya, Kato, Yasuhiko, Wada, Tadashi, Watanabe, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019738/
https://www.ncbi.nlm.nih.gov/pubmed/36928065
http://dx.doi.org/10.1371/journal.pone.0280421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019738/
https://www.ncbi.nlm.nih.gov/pubmed/36928065
http://dx.doi.org/10.1371/journal.pone.0280421

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