A Young Woman with Autosomal Dominant Hyper Immunoglobulin E (job’s) Syndrome Presenting with Acute Abdomen: a Case Report

BACKGROUND: Autosomal dominant hyper immunoglobulin IgE syndrome is a rare inherited condition that causes immune suppression. OBJECTIVE: This case report describes a severe case of liver abscess, caused by a cavity-forming infection, secondary to Job’s syndrome. CASE PRESENTATION: A 25-year-old fem...

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Autores principales: Verras, G Georgios-Ioannis, Mulita, Francesk, Chlorogiannis, David Dimitris, Liolis, Elias, Perdikaris, Ioannis, Perdikaris, Panagiotis, Bouchagie, Konstantinos, Akrida, Ioanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical Sciences of Bosnia and Herzegovina 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019861/
https://www.ncbi.nlm.nih.gov/pubmed/36937610
http://dx.doi.org/10.5455/medarh.2022.76.476-479
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author Verras, G Georgios-Ioannis
Mulita, Francesk
Chlorogiannis, David Dimitris
Liolis, Elias
Perdikaris, Ioannis
Perdikaris, Panagiotis
Bouchagie, Konstantinos
Akrida, Ioanna
author_facet Verras, G Georgios-Ioannis
Mulita, Francesk
Chlorogiannis, David Dimitris
Liolis, Elias
Perdikaris, Ioannis
Perdikaris, Panagiotis
Bouchagie, Konstantinos
Akrida, Ioanna
author_sort Verras, G Georgios-Ioannis
collection PubMed
description BACKGROUND: Autosomal dominant hyper immunoglobulin IgE syndrome is a rare inherited condition that causes immune suppression. OBJECTIVE: This case report describes a severe case of liver abscess, caused by a cavity-forming infection, secondary to Job’s syndrome. CASE PRESENTATION: A 25-year-old female patient was emergently referred to the surgical department, for the evaluation of acute, right-sided, upper abdominal pain, fever, and chills. The patient reported a past history of recurrent pulmonary infections as well as a prior diagnosis of Job’s syndrome. An abdominal CT scan revealed a large intrahepatic cystic mass, consistent with a hepatic abscess on the right liver lobe. The patient was started on a course of antibiotics and was admitted to the surgical ward for further treatment. After much deliberation, a multidisciplinary team comprised of general surgeons, gastroenterologists, and interventional radiologists, decided upon the guided drainage of the abscess. Two pigtail catheters were used to drain the cavities. Antibiotic use was de-escalated, the patient gradually recovered, and the reported abscesses were greatly reduced in size. After 14 days of treatment, the patient was successfully released home. CONCLUSION: In patients with a known history of the autosomal dominant hyper-IgE syndrome, presenting with acute abdominal pain, the liver abscess must be on the top of the differential diagnosis list.
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spelling pubmed-100198612023-03-17 A Young Woman with Autosomal Dominant Hyper Immunoglobulin E (job’s) Syndrome Presenting with Acute Abdomen: a Case Report Verras, G Georgios-Ioannis Mulita, Francesk Chlorogiannis, David Dimitris Liolis, Elias Perdikaris, Ioannis Perdikaris, Panagiotis Bouchagie, Konstantinos Akrida, Ioanna Med Arch Case Report BACKGROUND: Autosomal dominant hyper immunoglobulin IgE syndrome is a rare inherited condition that causes immune suppression. OBJECTIVE: This case report describes a severe case of liver abscess, caused by a cavity-forming infection, secondary to Job’s syndrome. CASE PRESENTATION: A 25-year-old female patient was emergently referred to the surgical department, for the evaluation of acute, right-sided, upper abdominal pain, fever, and chills. The patient reported a past history of recurrent pulmonary infections as well as a prior diagnosis of Job’s syndrome. An abdominal CT scan revealed a large intrahepatic cystic mass, consistent with a hepatic abscess on the right liver lobe. The patient was started on a course of antibiotics and was admitted to the surgical ward for further treatment. After much deliberation, a multidisciplinary team comprised of general surgeons, gastroenterologists, and interventional radiologists, decided upon the guided drainage of the abscess. Two pigtail catheters were used to drain the cavities. Antibiotic use was de-escalated, the patient gradually recovered, and the reported abscesses were greatly reduced in size. After 14 days of treatment, the patient was successfully released home. CONCLUSION: In patients with a known history of the autosomal dominant hyper-IgE syndrome, presenting with acute abdominal pain, the liver abscess must be on the top of the differential diagnosis list. Academy of Medical Sciences of Bosnia and Herzegovina 2022-12 /pmc/articles/PMC10019861/ /pubmed/36937610 http://dx.doi.org/10.5455/medarh.2022.76.476-479 Text en © 2022 Georgios-Ioannis Georgios-Ioannis Verras, Francesk Mulita, David Dimitris Chlorogiannis, Elias Liolis, Ioannis Perdikaris, Panagiotis Perdikaris, Konstantinos Bouchagier, Ioanna Akrida https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Verras, G Georgios-Ioannis
Mulita, Francesk
Chlorogiannis, David Dimitris
Liolis, Elias
Perdikaris, Ioannis
Perdikaris, Panagiotis
Bouchagie, Konstantinos
Akrida, Ioanna
A Young Woman with Autosomal Dominant Hyper Immunoglobulin E (job’s) Syndrome Presenting with Acute Abdomen: a Case Report
title A Young Woman with Autosomal Dominant Hyper Immunoglobulin E (job’s) Syndrome Presenting with Acute Abdomen: a Case Report
title_full A Young Woman with Autosomal Dominant Hyper Immunoglobulin E (job’s) Syndrome Presenting with Acute Abdomen: a Case Report
title_fullStr A Young Woman with Autosomal Dominant Hyper Immunoglobulin E (job’s) Syndrome Presenting with Acute Abdomen: a Case Report
title_full_unstemmed A Young Woman with Autosomal Dominant Hyper Immunoglobulin E (job’s) Syndrome Presenting with Acute Abdomen: a Case Report
title_short A Young Woman with Autosomal Dominant Hyper Immunoglobulin E (job’s) Syndrome Presenting with Acute Abdomen: a Case Report
title_sort young woman with autosomal dominant hyper immunoglobulin e (job’s) syndrome presenting with acute abdomen: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019861/
https://www.ncbi.nlm.nih.gov/pubmed/36937610
http://dx.doi.org/10.5455/medarh.2022.76.476-479
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