Mesenchymal stem cell suppresses the efficacy of CAR-T toward killing lymphoma cells by modulating the microenvironment through stanniocalcin-1

Stem cells play critical roles both in the development of cancer and therapy resistance. Although mesenchymal stem cells (MSCs) can actively migrate to tumor sites, their impact on chimeric antigen receptor modified T cell (CAR-T) immunotherapy has been little addressed. Using an in vitro cell co-cu...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Liu, Qingxi, Zhou, Sa, He, Hongpeng, Zhao, Mingfeng, Ma, Wenjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019890/
https://www.ncbi.nlm.nih.gov/pubmed/36779699
http://dx.doi.org/10.7554/eLife.82934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019890/
https://www.ncbi.nlm.nih.gov/pubmed/36779699
http://dx.doi.org/10.7554/eLife.82934

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