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Optimization of Albuminuria-Lowering Treatment in Diabetes by Crossover Rotation to Four Different Drug Classes: A Randomized Crossover Trial

OBJECTIVE: Renin–angiotensin system (RAS) inhibitors decrease the urinary albumin to creatinine ratio (UACR) but are ineffective in up to 40% of patients. We hypothesized that rotation through different drug classes overcomes RAS inhibitor resistance and tested this in a randomized crossover trial....

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Detalles Bibliográficos
Autores principales: Curovic, Viktor Rotbain, Jongs, Niels, Kroonen, Marjolein Y.A.M., Zobel, Emilie H., Hansen, Tine W., Sen, Taha, Laverman, Gozewijn D., Kooy, Adriaan, Persson, Frederik, Rossing, Peter, Heerspink, Hiddo J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020026/
https://www.ncbi.nlm.nih.gov/pubmed/36657986
http://dx.doi.org/10.2337/dc22-1699