Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis

There has been considerable scientific effort dedicated to understanding the biologic consequence and therapeutic implications of aberrant tryptophan metabolism in brain tumors and neurodegenerative diseases. A majority of this work has focused on the upstream metabolism of tryptophan; however, this...

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Detalles Bibliográficos
Autores principales: Kesarwani, Pravin, Kant, Shiva, Zhao, Yi, Prabhu, Antony, Buelow, Katie L., Miller, C. Ryan, Chinnaiyan, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020159/
https://www.ncbi.nlm.nih.gov/pubmed/36927729
http://dx.doi.org/10.1038/s41467-023-37170-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020159/
https://www.ncbi.nlm.nih.gov/pubmed/36927729
http://dx.doi.org/10.1038/s41467-023-37170-z

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