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Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis
There has been considerable scientific effort dedicated to understanding the biologic consequence and therapeutic implications of aberrant tryptophan metabolism in brain tumors and neurodegenerative diseases. A majority of this work has focused on the upstream metabolism of tryptophan; however, this...
Autores principales: | Kesarwani, Pravin, Kant, Shiva, Zhao, Yi, Prabhu, Antony, Buelow, Katie L., Miller, C. Ryan, Chinnaiyan, Prakash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020159/ https://www.ncbi.nlm.nih.gov/pubmed/36927729 http://dx.doi.org/10.1038/s41467-023-37170-z |
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