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IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity

B cells contribute to chronic inflammatory conditions as source of antibody-secreting plasma cells and as antigen-presenting cells activating T cells, making anti-CD20-mediated B cell depletion a widely used therapeutic option. B cells or B cell subsets may, however, exert regulatory effects, while...

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Detalles Bibliográficos
Autores principales: Geladaris, Anastasia, Häusser-Kinzel, Silke, Pretzsch, Roxanne, Nissimov, Nitzan, Lehmann-Horn, Klaus, Häusler, Darius, Weber, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020302/
https://www.ncbi.nlm.nih.gov/pubmed/36854993
http://dx.doi.org/10.1007/s00401-023-02552-6