Discovery of novel acetylcholinesterase inhibitors through integration of machine learning with genetic algorithm based in silico screening approaches

INTRODUCTION: Alzheimer’s disease (AD) is the most studied progressive eurodegenerative disorder, affecting 40–50 million of the global population. This progressive neurodegenerative disease is marked by gradual and irreversible declines in cognitive functions. The unavailability of therapeutic drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Mohd Imran, Taehwan, Park, Cho, Yunseong, Scotti, Marcus, Priscila Barros de Menezes, Renata, Husain, Fohad Mabood, Alomar, Suliman Yousef, Baig, Mohammad Hassan, Dong, Jae-June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020350/
https://www.ncbi.nlm.nih.gov/pubmed/36937207
http://dx.doi.org/10.3389/fnins.2022.1007389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020350/
https://www.ncbi.nlm.nih.gov/pubmed/36937207
http://dx.doi.org/10.3389/fnins.2022.1007389

Ejemplares similares