Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal

Background: Aging and oxidative stress are considered to be the proximal culprits of postmenopausal osteoporosis. Eldecalcitol (ED-71), a new active vitamin D derivative, has shown a good therapeutic effect on different types of osteoporosis, but the mechanism is unclear. This study focused on explo...

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Detalles Bibliográficos
Autores principales: Kou, Yuying, Rong, Xing, Tang, Rong, Zhang, Yuan, Yang, Panpan, Liu, Hongrui, Ma, Wanli, Li, Minqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020367/
https://www.ncbi.nlm.nih.gov/pubmed/36937895
http://dx.doi.org/10.3389/fphar.2023.1067085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020367/
https://www.ncbi.nlm.nih.gov/pubmed/36937895
http://dx.doi.org/10.3389/fphar.2023.1067085

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