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Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal
Background: Aging and oxidative stress are considered to be the proximal culprits of postmenopausal osteoporosis. Eldecalcitol (ED-71), a new active vitamin D derivative, has shown a good therapeutic effect on different types of osteoporosis, but the mechanism is unclear. This study focused on explo...
Autores principales: | Kou, Yuying, Rong, Xing, Tang, Rong, Zhang, Yuan, Yang, Panpan, Liu, Hongrui, Ma, Wanli, Li, Minqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020367/ https://www.ncbi.nlm.nih.gov/pubmed/36937895 http://dx.doi.org/10.3389/fphar.2023.1067085 |
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